The Blues have endured a disappointing season and are currently 12th in the Premier League, but they have returned to form recently and are unbeaten in their last ten top-flight matches.
Saints are also on a hot streak of their own, having won five and drawn one of their previous six, without conceding a goal in any of those games.
It makes for a mouthwatering clash when the sides meet, and it is one that midfielder Clasie is relishing, as Saints play the first of three matches in eight days.
"It's very important, but I think the most important thing is looking forward to Chelsea and then after that to the other games,” Clasie told Southampton’s official YouTube channel
about this upcoming run.
“Chelsea at home is a beautiful game to start after the break. It's a top team and they've got many good players. The last few weeks they are doing much better, but we have confidence and we have to look to ourselves.”
Saints can take additional belief from their performance at Stamford Bridge earlier in the season when they came from a goal down to triumph 3-1.
"If you beat them twice I think that is lovely for us,” added Clasie. “They are a big team. We trust each other and we go for it every day and every training session. We are looking forward to every game, at home and away, and hopefully we can win that game.”