Saints sit bottom of the Barclays Premier League after ten games, leading the gaffer to opt for a change of approach in the run-up to the next batch of fixtures.
"We've got players coming back to fitness and we're going to take the guys away for a couple of days in preparation," Adkins said during his pre-match media briefing this morning.
"We'll change things around a little bit and change the stimulus, which I think is important because it can become a bit of a 'Groundhog Day'.
"We've reached ten games and we were always going to look to have a break by changing the environment and the mindset so we are focused for the next game.
"I think it's good to change the routine, and take that into this weekend's important game.
"We've got to start getting points on the board and having the winning mentality that we've had for the last few years at the football club," he continued.
"We've just had ten games, so we've assessed where we are and accepted the situation. We'll keep moving forward.
"We can't do anything to affect the ten games we've had previously so we've put them to bed now. We'll move on and look forward to the next ones with positivity and a steely resolve.
"We've had to assess and address our aspirations at the start of the campaign. We're in a relegation dogfight, and we're fighting – everyone is well aware of that.
"People have got to be accountable and the players have got to take responsibility, as have every other member of staff.
"The supporters are behind the football club and behind the players when they go out on that pitch, and that's important.
"We're all going to work hard to make this a successful season for Southampton."
The gaffer confirmed that he has no new injury concerns after Monday's trip to West Bromwich Albion, where Gastón Ramírez made his return from a month-long lay-off.
Jack Cork will come into contention for his first top-flight appearance of the season having played the full 90 minutes of the Under-21s' win over Sunderland earlier this week.
Defender Frazer Richardson, who suffered a thigh injury again Fulham last month, will play for the Development Squad at Spurs on Monday.
Adkins also confirmed that goalkeeper Artur Boruc is available for selection following the Club's investigation into a complaint made against him during the home defeat to Spurs a fortnight ago.
"We've had a thorough investigation into the situation against Tottenham," said the manager.
"I didn't select him for the West Bromwich Albion game, but the investigation has now been concluded to the satisfaction of the Football Club.
"Artur is now back in contention for the remaining fixtures.
"We're under no illusions about the game we face at the weekend," Nigel said of Saturday's opponents, who currently sit in 11th place in the Premier League table.
"They've been good. They changed the manager in the summer but their style of play and their framework has stayed the same.
"They've had a good start having lost a couple of games then kicked on again."