Three days on from holding Sunderland to a draw at St Mary’s, the squad travels to South Yorkshire to take on the team currently propping up the Championship table, with the Tykes taking just one point from their opening four league games this season.
They are yet to record a win over 90 minutes this term, having got through the first round of the competition against Scunthorpe United on a penalty shoot-out.
Saints are chasing a fourth consecutive win against the Tykes, and are unbeaten in the last five games against Barnsley in all competitions.
Last year Southampton made it to the fourth round of this competition after beating Stevenage and Sheffield Wednesday, before losing 3-0 to Leeds United at Elland Road.
There has been only one previous League Cup meeting between the sides, which Saints won 2-1 in a third round tie at Oakwell in October 1997.
Barnsley defender Jean-Yves Mvoto is suspended after seeing red in the Tykes’ 5-2 defeat at Blackburn Rovers on Saturday.
However, the hosts could hand a debut to former Celtic winger Paddy McCourt.
Barnsley list ex-Saints Martin Cranie and Jacob Mellis amongst their squad, though the former is injured and will not feature this evening.
Dale Jennings, who scored against Saints for Tranmere Rovers in League One, has missed most of the Tykes’ opening games after being sent off on the first day of the season in a 4-0 defeat to Wigan Athletic.
For Saints, Morgan Schneiderlin is a doubt after coming off at half-time ion Saturday’s 1-1 draw with Sunderland. Luke Shaw also took a knock, and is unlikely to feature.
The likes of Jack Cork, Steven Davis and Emmanuel Mayuka, who have had limited game time so far this season, could all come into contention.
A number of Development Squad players missed yesterday’s Under-21sfixture at Reading, and they could also therefore be involved in the squad tonight.
The opening-day game of 2011/12 saw Saints win 1-0 at Oakwell with David Connolly getting the goal. In the reverse fixture at St Mary’s later that season, a brace of goals from Adam Lallana either side of bhalf-time secured a 2-0 success for the hosts.
Barnsley’s last win against Saints came in September 2007 with a 3-2 victory at St Mary’s. Marek Saganowski and Inigo Idiakez were on the scoresheet for Saints.
The match will be refereed by Scott Duncan, who will be assisted by Robert Atkin and Nick Hobbis. Gary Sutton is the fourth official.
Tickets for this match remain on general sale. You can buy yours at Oakwell right up until kick-off at 7.45pm this evening.
You can listen to live commentary courtesy of BBC Solent on Saints Player
, where you can keep up to date with all the stats and scores from around the country.
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